allergy immunology

8 notes · index updated 2026-07-09

anaphylaxis & acute allergic reactions urticaria & angioedema drug allergy immunodeficiency mastocytosis & mast cell disease eosinophilia

anaphylaxis & acute allergic reactions

1

anaphylaxis WAO/NIAID diagnostic criteria, epinephrine dosing (IM & IV), biphasic reaction risk, differential diagnosis, disposition
6 min 2026-07-09

urticaria & angioedema

2

urticaria and angioedema histaminergic vs bradykinin-mediated, CSU management, antihistamine up-dosing, approach to angioedema
5 min 2026-07-09
hereditary angioedema bradykinin-mediated angioedema, HAE classification and diagnosis (C4/C1-INH), acute treatment (Berinert dosing), short-term and long-term prophylaxis, ACE inhibitor angioedema
5 min 2026-07-09

drug allergy

2

immunodeficiency

1

approach to immunodeficiency secondary vs primary, pattern recognition by organism/immune defect, initial workup (Ig levels, vaccine responses, HIV), when to refer, practical tips (pre-rituximab baseline, CD4 thresholds)
4 min 2026-07-09

mastocytosis & mast cell disease

1

mastocytosis KIT D816V, WHO diagnostic criteria (major + minor), cutaneous vs systemic classification, B/C-findings, tryptase interpretation, stepwise mediator management, avapritinib for advanced SM, trigger avoidance
5 min 2026-07-09

eosinophilia

1

approach to eosinophilia differential (NAACP: neoplasm, allergy, autoimmune, infection, parasites), clonal vs reactive workup, HES subtypes, end-organ damage assessment, stepwise management
4 min 2026-07-09