haematology
8 notes
topics
- iron deficiency — diagnosis (context-specific thresholds), oral vs. IV repletion, HMB workup, Fishbane reactions, HF evidence
- multiple myeloma — plasma cell malignancy, CRAB/SLiM criteria, induction therapy
- acute leukaemia — AML/ALL/APL recognition, leukostasis, differentiation syndrome, TLS, APL coagulopathy
- antiphospholipid syndrome — Sapporo criteria, triple positivity, warfarin (not DOACs), CAPS triple therapy, obstetric APS
- deep vein thrombosis — Wells score, CUS algorithm, DOAC selection (COBRRA), duration by risk category, pregnancy VTE, dose-reduction evidence (API-CAT/RENOVE)
- hereditary thrombophilia — when (and when not) to test, assay interference (DOACs, inflammation, pregnancy), specific defects, prophylaxis in pregnancy and on hormones
- tumour lysis syndrome — Cairo-Bishop criteria, risk stratification, rasburicase (dosing, G6PD contraindication, lab artefact), electrolyte management, dialysis indications
- febrile neutropaenia — 60-minute antibiotic bundle, MASCC risk stratification, antifungal escalation, de-escalation by ANC vs. time-based approach, Duffy null, medication-induced neutropaenia patterns
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